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Nevertheless, multiple degradation-resistant and structurally distinct GLP-1RAs do not generate the same GLP-1 metabolites yet reduce blood pressure, increase heart rate, inhibit enterocyte chylomicron secretion and reduce the extent of myocardial infarction in rats and mice through mechanisms requiring the canonical GLP-1R [99, 105,106,107,108]

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doi: 10.1016/j.tem.2016.03.017 81 SlleyEKunSSzijrtIAKertszMWittmannIMolnrGA

There are three main anatomic structures in the medial side of the knee, with the superficial medial collateral ligament being the largest and strongest